Description
Product Characteristics: 2 COP antibody, Coat protein nonclathrin gamma 2 cop antibody, Coatomer protein complex subunit gamma 2 antibody, Coatomer subunit gamma 2 antibody, Coatomer subunit gamma-2 antibody, COPG 2 antibody, Copg2 antibody, COPG2_HUMAN antibody, DKFZp761N09121 antibody, FLJ11781 antibody, Gamma 2 coat protein antibody, Gamma 2 COP antibody, Gamma-2-coat protein antibody, Gamma-2-COP antibody
Target Information: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins\, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity)